Endocrine Abstracts

Aim: Lipedema is a painful fat disorder that affects ~11% of the female population, characterized by bilateral, disproportionate accumulation of subcutaneous adipose tissue predominantly in the lower body. The initial manifestations of lipedema arise in phases of hormonal change (puberty, pregnancy, menopause). The pathophysiology of lipedema is unclear. The putative causes proposed include altered adipogenesis, microangiopathy, and disturbed lymphatic microcirculation The dis...

Aim: Lipedema is a painful fat disorder that affects 11-17% of woman. The diagnosis is based on typical clinical features: bilateral symmetrical disproportionate fatty tissue hypertrophy on the limbs sparing of the hands and feet, feeling of heaviness and tension, easy bruising, transient edema and pain in the affected areas. There are three clinical stages (1, 2 and 3) that refer primarily to appearance of the skin, texture of subdermal tissue and the presenc...